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On Demand Webinar

X-Ray Powder Diffraction: Pharmaceutical Solid-State Characterization

Overview of XRPD with discussion topics that include common instrument geometries, best practices for sample preparation, and data analysis examples.

X-Ray Powder Diffraction (XRPD) is an essential technique in the pharmaceutical sciences. Pharmaceutical Solid-State Characterization includes applications like positive material identification, quantification of APIs and excipients, and determination of degree of crystallinity or amorphous. Because diffraction relies on long-range ordering within a material, XRPD can provide insights into structural polymorphism, supplementing the molecular information gathered from NMR and spectroscopic techniques.

This webinar will explore the topic of Pharmaceutical Solid-State Characterization, and how the Bruker D2 PHASER Benchtop XRD delivers data quality and collection speed that, up to recently, was thought impossible with a benchtop XRD system. Due to its compact size, low weight, and ease-of-use design, the system is conveniently mobile, without the need for complicated infrastructure, large, heavy-load work benches, or vendor installation and alignment. A standard power outlet and a few minutes are all that is required to take they system from fully packaged to outstanding results.

The D2 PHASER is a portable desktop XRD instrument for pharmaceutical solid-state characterization, research and quality control. It is for instance possible to investigate crystal structures applying the fundamental parameters approach in the TOPAS software, nano-structures for fast and reliable SAXS measurements, or micro-structures (crystallite size).

Key webinar takeaways:

  • Overview of X-Ray Powder Diffraction
  • Common instrument geometries
  • Best practices for sample preparation
  • Examples of data analysis examples

PRESENTED BY:

Nathan Henderson, PhD

Nathan Henderson, PhD

Senior Application Scientist,

Bruker Corporation

Nathan is a Senior Application Scientist for Bruker’s X-ray division with a specialization in powder diffraction techniques. His research interests include structure-property relationships in functional oxides and intermetallics, quantitative mineralogy, and non-ambient diffraction. He received his B.S. in Chemistry from Louisiana State University and his Ph.D. in Materials Chemistry from Penn State University.

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